In Mortal Kombat: De Shaolin Monks, players control Liu Kang and Kung Lao as they navigate through various levels, fighting against hordes of enemies and confronting iconic Mortal Kombat characters. The gameplay revolves around melee combat, with an emphasis on martial arts and acrobatic moves. Players can execute a range of attacks, combos, and special moves, including the infamous "fatalities." The game also features a variety of boss battles, requiring players to employ strategy and quick reflexes to emerge victorious.